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Hepatocarcinoma fibrolamelar un tumor de adultos jóvenes poco frecuente. . Dentro de los diagnósticos diferenciales se debe considerar la HNF, CHC. Protocolo de diagnóstico diferencial de las lesiones ocupantes de espacio en el hígado cirrótico Clinical management of hepatocellular carcinoma. Su diagnóstico suele ser tardío, ya que se presenta en pacientes jóvenes, sin . a las del hepatocarcinoma en la que es necesario un diagnóstico diferencial.

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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Adenomas are composed of hepatocytes containing glycogen and lipids surrounded by a capsule.

Finally, the hepatobiliary phase is acquired 20 minutes after gadoxetic acid administration 1diagnostcio. Current problems in diagnostic radiology ; 36 6: The utilization of hepatobiliary contrast agents may reduce the necessity of invasive diagnostic procedures as well as of further investigation with other imaging methods, and imaging follow-up, reducing costs and the anxiety of both patients and medical team.

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All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. FNH is a benign lesion that does not require any intervention, while adenoma presents risk for malignization, necrosis and bleeding which might require emergency surgery.

The avascular lesion arrowhead is secondary to post-treatment disgnostico. Female, year-old patient presenting with colon cancer. The differentiation between Hepatocacinoma and perfusion alterations may also represent a diagnostic challenge. The imaging evaluation of the biliary system has been approached by a series of publications in the Brazilian radiological literature 24 – On the other hand, the lesions showed homogeneous hepatobiliary contrast uptake, hence the highest likelihood of the diagnosis of multiple FNHs.


Primary liver carcinoma arising in people younger than 30 years. As a result, the healthy hepatic tissue remains hyperintense and the metastasis, hypointense, which facilitates its detection 12. The usual dynamic study with arterial, portal and delayed phases is also performed with such contrast agents. This article has been cited by other articles in PMC. A fraction of hepatobiliary contrast agent is excreted by cMOAT into the biliary canaliculi multispecific canalicular organic anion transporter 1.

Hepatology ; 39 3: Radiology ; 3: Calcification in focal nodular hyperplasia: The hepatobiliary contrast may contribute to the diagnosis of cholecystitis as the gallbladder is not filled by the contrast medium, differently from its habitual behavior with other contrast agents. Such contrast agents shortens the T1 relaxation time of the bile and allows for the performance of a high-resolution T1-weighted cholangiography 4.

Fibrolamellar hepatocellular carcinoma: a case report

Abstract Fibrolamellar hepatocarcinoma is a rare neoplasm diagnosed by computed tomography and confirmed by anatomopathological examination. Hemangiomas do not contain functioning hepatocytes so uptake of this contrast medium is not observed. The use of hepatobiliary contrast agents may reduce the need for invasive diagnostic procedures and further investigations with other imaging methods, besides the need for imaging follow-up.

Journal List Radiol Bras v. Hepatobiliary contrast uptake by HCC also diferencixl on its differentiation stage. MR Imaging of hepatocellular carcinoma in the cirrhotic liver: The previous knowledge of the biliary anatomy and its variations becomes increasingly important in the preoperative planning, considering the complexity of the hepatic anatomy as well as of the more refined surgical techniques, which reduces the occurrence of postoperative complications 4.


Adverse effects of hepatobiliary contrast agents rarely occur and, if present, are similar to the ones reported in the use of extra-cellular diferencia.

Fibrolamellar hepatocellular carcinoma presenting diagnostuco Budd-Chiari syndrome, right atrial thrombus, and pulmonary emboli. Additionally, hepatobiliary contrast agents contribute to the diagnosis of small, benign focal lesions frequently found in patients with neoplasias, particularly FNH Figure 8.

The lesions in segments VII and VIII arrows are similar, with marked hypersignal on T2-weighted, hyposignal on T1-weighted sequence, and nodular, peripheral and discontinuous uptake in the arterial phase, a characteristic of hemangiomas. Patients with cirrhosis Child A or B do not present hepattocarcinoma significant alteration in the total clearance of hepatobiliary contrast agents; but in cirrhosis Child C, there is a decreased total clearance and increased half life, with compensatory increase of renal excretion 8.

Further potential hepatobiliary contrast applications include the evaluation of the functional hepatic reserve before partial hepatectomy; evaluation of live donor’s hepatic function as well as evaluation of early liver failure after hepatocarcinoms 4.

Computed body tomography with MRI correlation.

Imaging evaluation of congenital cystic lesions of the biliary tract. In cirrhosis, the hepatobiliary contrast uptake by the nodules depends on their differentiation stage and on the presence of functioning hepatocytes. Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: Find articles by Daniella Braz Parente.

Journal of hepatology ; 56 4: Pure and mixed fibrolamellar hepatocellular carcinomas differ in natural history and prognosis after complete surgical resection. J Korean Soc Radiol. Imaging of fibrolamellar hepatocellular carcinoma.